| Main Title |
Arabidopsis Assay for Mutagenicity. |
| Author |
Gichner, T. ;
Badayev, S. A. ;
Demchenko, S. I. ;
Relichova, J. ;
Sandhu, S. S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Office of Health Research. ;Institute of Experimental Botany, Prague (Czech Republic). ;Akademiya Nauk SSSR, Moscow. Inst. Fizicheskoi Khimii. ;Akademiya Nauk Tadzhikskoi SSR, Dushanbe. Dept. of Genetics. |
| Publisher |
c1994 |
| Year Published |
1994 |
| Report Number |
EPA/600/J-94/523; |
| Stock Number |
PB95-148854 |
| Additional Subjects |
Bioassay ;
Plants(Botany) ;
Pollutant identification ;
Toxic substances ;
Environmental effects ;
International cooperation ;
Chemical compounds ;
Mutagens ;
Sodium azides ;
Validation ;
Azides ;
Sulfur compounds ;
Nitroso compounds ;
Reprints ;
Arabidopsis assay ;
Methane sulfonate/ethyl ;
Ureo/N-methyl-N-nitroso ;
Glycerol/azido ;
Maleic hydrazide
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB95-148854 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
Four laboratories, two in Czechoslovakia (Brno and Prague) and two in USSR (Moscow and Duschanbe), participated in the International Program On Chemical Safety (IPCS) Collaborative Study to evaluate the utility of the most commonly used plant test systems, including the Arabidopsis thaliana assay, for assessing the mutagenic potential of environmental agents. Out of the five compounds evaluated in the Arabidopsis assay, 3 compounds; i.e., ethyl methanesulfonate, N-methyl-N-nitrosourea, and 3-azidoglycerol, were reported by all four participating laboratories to be mutagenic. Sodium azide (NaN3) demonstrated negative response in all four laboratories; whereas, maleic hydrazide was reported to be weakly mutagenic by one laboratory and no mutagenic response by the other three laboratories. (Copyright (c) 1994 Elsevier Science B.V.) |
| Supplementary Notes |
Pub. in Mutation Research 310, n2 p249-256 Nov 94. See also PB83-225078. Prepared in cooperation with Institute of Experimental Botany, Prague (Czech Republic)., Akademiya Nauk SSSR, Moscow. Inst. Fizicheskoi Khimii., and Akademiya Nauk Tadzhikskoi SSR, Dushanbe. Dept. of Genetics. |
| Highlights Notes |
%AUT:P. D. /Usmanov ;O. /Usmanova ;J. /Veleminsky |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Arabidopsis Assay for Mutagenicity. |
| Category Codes |
57C; 57Y; 57H; 68 |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
503415342 |
| Origin |
NTIS |
| Type |
CAT |
