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Main Title Interim Report of Mouse Skin-Painting Test Results with Aromatic Petroleum Pitch with Cover Letter dated 07/14/80.
CORP Author Standard Oil Co. (Ohio), Cleveland.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 21 Jul 1980
Year Published 1980
Report Number 8HEQ-0780-0353;
Stock Number OTS-0204860
Additional Subjects Skin diseases ; Mice ; Toxicity ; Solvents ; Dosage ; Carcinoma ; Tumors ; Aromatics ; Body fluids ; Toluene ; Laboratory tests ; Exposure ; Bioavailability ; Laboratory animals ; Aromatic petroleum pitch ; Standard Oil Company
Library Call Number Additional Info Location Last
NTIS  OTS-0204860 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 50p
Abstract This report summarizes significant data obtained after 59 weeks of a projected lifetime mouse skin-painting study instituted to assay the carcinogenic potential of products produced from the oxidative condensation of an intermediate clarified oil solvent extract (CAS Registry No. 64741-62-4). The results obtained support the conclusion that at high dose levels when all or a portion of the test materials are made bioavailable via salvation in toluene, skin tumors are induced. The bioavailability of the solid test materials via solvation in normal body fluids (e.g. sweat, saliva, gastro-intestinal fluids, etc.) was not addressed in this study.
Supplementary Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC.
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Category Codes 57Y; 57E
NTIS Prices PC A04/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 009400320
Origin NTIS
Type CAT