| Main Title |
Dermal Carcinogenesis Assay in C3H/HEJ Mice with Cover Letter dated 07/18/86. |
| CORP Author |
Exxon Corp., East Millstone, NJ. Research and Environmental Health Div.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
24 Jul 1986 |
| Year Published |
1986 |
| Report Number |
8EHQ-0886-0306/0316; |
| Stock Number |
OTS-0200627-1 |
| Additional Subjects |
Skin(Anatomy) ;
Carcinogenesis ;
Mice ;
Toxicology ;
Oncogenes ;
Skin neoplasms ;
Assaying ;
Body weight ;
Laboratory animals ;
Dermal growth ;
Chemical analysis ;
Death ;
Clinical observation ;
Dose-response relationships ;
Evaluation ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200627-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1081p |
| Abstract |
The objective of this study was to evaluate the oncogenic potential of test materials MRD-82-18, MRD-82-57A, MRD-82-142, and MRD-82-153 through MRD-82-157, MRD-82-19A, MRD-82-19A, and MRD-82-19C when applied to mouse skin. The study was initiated with 510 male C3H/HeJ mice which were divided into 9 groups of 50 mice each and 3 groups of 20 mice each. The animals of Groups 1 through 11, and 14 through 16 received 25 micro liters of undiluted test material to the clipped backs 3 times per week until death of the animals; Group 13 served as a shaved control which did not received any test material but was assigned test material number MRD-82-158, and Group 12 served as the negative control receiving 25 microliters of MRD-82-157. (All statistical analyses were run against Group 12, the control group). |
| Supplementary Notes |
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| Availability Notes |
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| Category Codes |
57Y; 57O |
| NTIS Prices |
PC A99/MF E11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
035501260 |
| Origin |
NTIS |
| Type |
CAT |
