Main Title |
Initial Submission: Letter from Dupont Chemical to USEPA regarding Embryo-Fetal and Terotogenicity Study of Silane in Rats with Cover Letter and Attachments dated 08/20/1992. |
CORP Author |
Du Pont de Nemours (E.I.) and Co., Wilmington, DE.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
8EHQ-0892-10197 |
Stock Number |
OTS0570779 |
Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Silane(bis(4- fluropheny))(methyl) (1H-1 ;
2 ;
4-triazol) ;
Reproduction ;
Fertility effects ;
Combined teratogenicity ;
Reproductive effects ;
Mammals ;
Rats ;
Oral ;
Gavage ;
CAS No 85509-19-9
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0570779 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
11p |
Abstract |
Rats were dosed at levels of 0, 10, 50, and 250 mg/kg; maternal toxicity and deaths occurred at 250 mg/kg; a significant increase in the incidence of fetuses with cleft palate and with absence of renal papilla was seen at 250 mg/kg. Embryo-fetal toxicity was noted at all levels tested (decreased fetal weight, increased fetal death at 250 mg/kg; and increase incidence of skeletal variations at 10 mg/kg and above). |
Supplementary Notes |
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Availability Notes |
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PUB Date Free Form |
24 Aug 1992 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A03/MF A03 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
010503020 |
Origin |
NTIS |
Type |
CAT |