| Main Title |
Acute Oral Toxicity (LD50) Study in Rats with Cover Letter and Attachments. |
| CORP Author |
Velsicol Chemical Corp., Chicago, IL. ;International Research and Technology Corp., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
19 Jun 1978 |
| Year Published |
1978 |
| Report Number |
8EHQ-0678-0198; |
| Stock Number |
OTS-0200382 |
| Additional Subjects |
Toxicity ;
Oral dosage ;
Rats ;
Males ;
Females ;
Laboratory animals ;
Reproduction(Biology) ;
Gavage ;
Body weight ;
Sex ;
Mortality ;
Corn oil ;
Velsicol Chemical Corporation
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200382 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
21p |
| Abstract |
Thirty male and 30 female rats of the Charles River CD strain (obtained from The Charles River Breeding Laboratories, Incorporation, and Portage, Michigan) weighing from 200 to 250 grams were used for this study. The rates were housed by sex, in groups of 5 rats per cage, in hanging wire-mesh cages in temperatures and humidity controlled quarters. They were maintained in accordance with the recommendations contained in H.E.W. Publication No. 74-23 (N.I.H.) entitled 'Guide for the Care and Use of Laboratory Animals.' The rats were conditioned for a minimum of 35 days prior to study initiation. Water and Purina Laboratory Chow were available ad libitum, except for an overnight period of approximately 18 hours immediately preceding oral administration during which food, but not water, was withheld. The test material was administered orally by gavage as a suspension in corn oil at the following dosage levels to male and female rats: 631, 1000, 1585, 2512, 3980 and 6308 mg/kg. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y |
| NTIS Prices |
PC A03/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
035500810 |
| Origin |
NTIS |
| Type |
CAT |
