| Main Title |
Physiological Methods for Assessment of Timethyltin Exposure. |
| Author |
Dyer, Robert S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1982 |
| Report Number |
EPA-600/J-82-323; |
| Stock Number |
PB83-223610 |
| Additional Subjects |
Toxicology ;
Assessments ;
Senses ;
Pathology ;
Exposure ;
Reprints ;
Tin/trimethyl ;
Limbic system ;
Neurotoxicity
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-223610 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Trimethyltin has been reported to produce morphological alterations in the brain which are primarily restricted to the limbic system. A variety of physiological measures of limbic system integrity are discussed in terms of their ability to detect TMT-induced dysfunction. In addition, several measures of sensory system dysfunction are discussed. It is concluded that limbic system dysfunction induced by this compound is detected more efficiently by intrahippocampal evoked potentials than by more gross measures of dysfunction. It is also concluded that relying upon preliminary descriptions of pathological alterations to direct physiological studies may provide an incomplete description of neurotoxicity. |
| Supplementary Notes |
Pub. in Neurobehavioral Toxicology and Teratology, v4 p659-664 1982. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Physiological Methods for Assessment of Timethyltin Exposure. |
| PUB Date Free Form |
1982 |
| Category Codes |
6T; 6E; 57Y; 57O |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
321722196 |
| Origin |
NTIS |
| Type |
CAT |
