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Main Title On the Question of the Mode of Action of the Bronchosecretolytic Agent, N-Cyclohexyl-N-Methyl-(2-Amino-3, 5-Dibromobenzyl)-Ammonium Chloride.
Author Eigelsreiter, H. ; Mair., M. ;
CORP Author National Institutes of Health, Bethesda, Md. Translation Unit.;Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1974
Report Number NIH-74-05C; EPA-TR-84-74;
Stock Number PB-237 908-T
Additional Subjects Muscle relaxants ; Bronchi ; Secretion ; Drugs ; Respiratory system ; Pharmacology ; West Germany ; Translations ;
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NTIS  PB-237 908-T Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract Although it appears to be certain that N-Cyclohexyl-N-methyl-(2-amino-3, 5-dibromobenzy)-ammonium chloride (Bisolvon) has an expectoration-promoting effect in animals, and human beings, the mechanism of action has not been thoroughly elucidated. Beside the reduction of viscosity of the bronchial secretion and a considerable increase in the granula of the secretion and of lysosomes in the caliciform cells, there also exists a dispute over an increased absorption from the bronchial tract. In the present examination an experiment was undertaken for the purposes of further clarification of the mechanism of action of Bisolvon.
Supplementary Notes Trans. of Arzneimittel-Forschung (West Germany) v17 p353-355 1967.
Highlights Notes *Bisolvon, Antispasmodic agents.
Title Annotations +++On the Question of the Mode of Action of the Bronchosecretolytic Agent, N-Cyclohexyl-N-Methyl-(2-Amino-3, 5-Dibromobenzyl)-Ammonium Chloride--Translation.
PUB Date Free Form 1974
Category Codes 06O
NTIS Prices PC A02/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 326596562
Origin NTIS
Type CAT