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Main Title Comparison of Mutagenic Activities of Several Peroxyacyl Nitrates.
Author Kleindienst, T. E. ; Shepson, P. B. ; Smith, D. F. ; Hudgens, E. E. ; Nero, C. M. ;
CORP Author NSI Technology Services Corp., Research Triangle Park, NC.;Environmental Protection Agency, Research Triangle Park, NC. Atmospheric Research and Exposure Assessment Lab.
Publisher c1990
Year Published 1990
Report Number EPA-68-02-4443; EPA/600/J-90/464;
Stock Number PB91-183251
Additional Subjects Mutagens ; Comparative evaluations ; Dose-response relationships ; Salmonella typhimurium ; Mutagenicity tests ; Reprints ; Peroxyacyl nitrates
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NTIS  PB91-183251 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Abstract Salmonella typhimurium strain TA100 was exposed to a series of peroxyacyl nitrates including peroxyacetyl nitrate (PAN), peroxypropionyl nitrate (PPN), peroxybutyryl nitrate (PBN), peroxybenzoyl nitrate (PBzN), and chloroperoxyacetyl nitrate (CPAN). Gas phase concentrations for the individual exposures were in the high ppbv range. The dose was determined from the deposition rate and measured from the net decrease of the test compound in the exposure chamber and the exposure time. The mutagenic activity for each compound determined from the dose-response relationship gave values ranging from 250 (PBN) to 6570 (PBzN) revertants/micromol. The difficulties of quantifying the actual gas-phase chemical dose the bacteria are exposed to in this variant of the Ames Test are delineated. (Copyright (c) 1990 Wiley-Liss, Inc.)
Supplementary Notes Pub. in Environmental and Molecular Mutagenesis, v16 p70-80 1990. Sponsored by Environmental Protection Agency, Research Triangle Park, NC. Atmospheric Research and Exposure Assessment Lab.
NTIS Title Notes Journal article.
Title Annotations Reprint: Comparison of Mutagenic Activities of Several Peroxyacyl Nitrates.
Category Codes 57Y; 57F
NTIS Prices PC A03/MF A01
Primary Description 600/09
Document Type NT
Cataloging Source NTIS/MT
Control Number 119321732
Origin NTIS
Type CAT