||Evaluation of the potential carcinogenicity of saccharin (81-07-2) /
||Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
|| U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;
||EPA/600/8-91/177; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-172
Aromatic compounds--Carcinogenicity. ;
Risk assessment ;
Public health ;
Hazardous materials ;
Dose-response relationships ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||30 pages ; 28 cm
||Saccharin is a possible human carcinogen, classified as weight-of-evidence Group C under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'Limited', and the evidence from human studies is 'Inadequate'. The potency factor (F) for saccharin is estimated to be 0.007 (mg/kg/day)-1, placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, saccharin is assigned a 'LOW' hazard ranking.
||Cover title. "June 1988." Includes bibliographical references. Microfiche.
||Washington, D.C. :
||Prepared in cooperation with Environmental Monitoring and Services, Inc., Washington, DC. Sponsored by Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
|Corporate Au Added Ent
||United States. Environmental Protection Agency. Office of Health and Environmental Assessment. Carcinogen Assessment Group.
|PUB Date Free Form
||PC A03/MF A01
|OCLC Time Stamp
|OCLC Rec Leader
||01188nam 2200265Ka 45020