| Main Title |
Aspirin Use and Lung, Colon, and Breast Cancer Incidence in a Prospective Study. |
| Author |
Schreinemachers, D. M. ;
Everson, R. B. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1994 |
| Year Published |
1994 |
| Report Number |
EPA/600/J-94/395; |
| Stock Number |
PB95-126504 |
| Additional Subjects |
Aspirin ;
Breast neoplasms ;
Pulmonary neoplasms ;
Colorectal neoplasms ;
Incidence ;
Prospective neoplasms ;
Cohort studies ;
Risk factors ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB95-126504 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
A large body of experimental data and several recent epidemiologic studies indicate that aspirin use may decrease cancer risk. The experimental studies found effects at many anatomic sites, whereas the epidemiologic studies saw the greatest effect on mortality from digestive cancers. To provide further human data, the authors examined the associated between aspirin use and cancer risk using data from the National Health and Nutrition Examination Survey I (NHANES I) and the NHANES I Epidemiologic Follow-Up Studies (NHEFS). Characterization of aspirin use was based on questions in the baseline interview asking whether subjects used aspirin during the previous 30 days. Data were available from 12,668 subjects age 25-74, at time of initial examination for NHANES I, who were followed for an average of 12.4 years. Among these subjects, 1,257 were diagnosed with cancer more than 2 years after their NHANES I examination. Incidence of several cancers was lower among persons who reported aspirin use: the incidence rate ratios (and 95% confidence intervals) for all sites combined were 0.83 (0.74-0.93), lung cancer 0.68 (0.49-0.94), breast cancer in women 0.70 (0.50-0.96), and colorectal cancer in younger men 0.35 (0.17-0.73). These findings were not readily explained by potentially confounding factors. The data suggest an association between aspirin consumption and decreased cancer incidence at several cancer sites. (Copyright (c) 1994 Epidemiology Resources Inc.) |
| Supplementary Notes |
Pub. in Epidemiology, v5 n2 p138-146 Mar 94. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Aspirin Use and Lung, Colon, and Breast Cancer Incidence in a Prospective Study. |
| Category Codes |
57E; 57U |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
500617503 |
| Origin |
NTIS |
| Type |
CAT |
