| Main Title |
Enhancement of Experimental Respiratory Infection following Nickel Inhalation. |
| Author |
Adkins, Jr., B. ;
Richards, J. H. ;
Gardner, D. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1979 |
| Report Number |
EPA-600/J-79-150; |
| Stock Number |
PB83-193490 |
| Additional Subjects |
Respiratory diseases ;
Nickel chloride ;
Respiration ;
Streptococcal infections ;
Mortality ;
Responses ;
Reprints ;
Air pollution effects(Animals)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-193490 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
The effects of nickel chloride inhalation on the enhancement of experimentally induced streptococcal infections were studied. Exposure to nickel chloride for 2 hr produced significant enhancement in mortality. This response was observed for 24 hr after the nickel chloride exposure. A delayed clearance response of inhaled streptococci, also observed in the nickel-treated mice, supported the mortality data. Several parameters involving pulmonary cells obtained by in situ lavage 24 hr after nickel chloride exposure were also studied; no reduction in total cell yield, viability, or cellular composition was observed. A significant reduction in phagocytic capability, as compared to that of control animal cells, was observed in alveolar macrophages obtained 24 hr after nickel chloride exposure. |
| Supplementary Notes |
Pub. in Environmental Research 20, p33-42 1979. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Enhancement of Experimental Respiratory Infection following Nickel Inhalation. |
| PUB Date Free Form |
c1979 |
| Category Codes |
6T; 6E; 57Y; 57E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
321645207 |
| Origin |
NTIS |
| Type |
CAT |
