| Main Title |
Macrophage Damage in Relation to the Pathogenesis of Lung Diseases. |
| Author |
Brain, Joseph D. ;
|
| CORP Author |
Harvard School of Public Health, Boston, MA.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1980 |
| Report Number |
EPA-R-805091; EPA-600/J-82-063; |
| Stock Number |
PB82-249269 |
| Additional Subjects |
Pathology ;
Respiratory diseases ;
Migrations ;
Behavior ;
Reprints ;
Lung diseases ;
Macrophages ;
Immune responses
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB82-249269 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
Pulmonary macrophages are important since their migratory patterns and behavior are often pivotal events in the pathogenesis of pulmonary disease. Alveolar macrophages act to decrease the probability of particle penetration through epithelial barriers, and their phagocytic and lytic potentials provide most of the known bactericidal properties of the lungs. Macrophages are also involved in immune responses and in defense against neoplasms. Increased inert or infectious particles stimulate the recruitment of additional macrophages. Most free cells containing particles eventually reach the airways and are quickly carried to the pharynx and swallowed. |
| Supplementary Notes |
Pub. in Environmental Health Perspectives, v35 p21-28 1980. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Macrophage Damage in Relation to the Pathogenesis of Lung Diseases. |
| PUB Date Free Form |
Apr 80 |
| Category Codes |
6E; 57O |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323822182 |
| Origin |
NTIS |
| Type |
CAT |
