| Main Title |
Mucociliary Clearance of Inhaled Particles Measured at 2 h after Ozone Exposure in Humans. |
| Author |
Gerrity, T. R. ;
Bennett, W. D. ;
Kehrl, H. ;
DeWitt, P. J. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Human Studies Div. ;North Carolina Univ. at Chapel Hill. Center for Environmental Medicine and Lung Biology. |
| Publisher |
25 Sep 91 |
| Year Published |
1991 |
| Report Number |
EPA/600/J-93/402; |
| Stock Number |
PB93-236396 |
| Additional Subjects |
Ozone ;
Air pollution effects(Humans) ;
Toxicity ;
Lung ;
Respiratory function tests ;
Mucus ;
Air ;
Comparison ;
Biological transport ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB93-236396 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Acute exposure of humans to ozone is known to acutely cause pulmonary function decrements, inflammation, and increased permeability of pulmonary epithelium. Fifteen healthy male and female nonsmoking subjects were exposed, on different occasions, to clean air and 0.4 ppm ozone for 1 hour while they exercised continuously. Pulmonary function was measured immediately before and after exposure and 90 min and 24 hours after exposure. Each subject returned the next day for a final particle retention measurement. Despite significant changes in pulmonary function, there was no difference in mean whole lung retention time of particles between clean air and ozone exposures, indicating that mucociliary transport is unaffected by ozone exposure when it is measured 2 hours after exposure. |
| Supplementary Notes |
Pub. in Jnl. of Applied Physiology, v74 n6 p2984-2989 Jun 93. See also PB89-110548. Prepared in cooperation with North Carolina Univ. at Chapel Hill. Center for Environmental Medicine and Lung Biology. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Mucociliary Clearance of Inhaled Particles Measured at 2 h after Ozone Exposure in Humans. |
| Category Codes |
68G; 68A; 57Y; 57S |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
330925780 |
| Origin |
NTIS |
| Type |
CAT |
