| Main Title |
Results of Range Finding Toxicological Test on Three Samples of 4-tert Octyl Phenol. |
| CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
40-5462011 |
| Stock Number |
OTS0527942 |
| Additional Subjects |
Toxicology ;
Health effects ;
4-(1 ;
1 ;
3 ;
3-tetramethylbutyl)phenol ;
Acute Toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Primary Eye Irritation ;
Rabbits ;
Dermal ;
Primary Dermal Irritation ;
Toxic substances ;
Laboratory animals ;
CAS No 140-66-9
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0527942 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
15p |
| Abstract |
4-(1,1,3,3-Tetramethylbutyl)phenol (TMBP) was evaluated for acute toxic effects. Summary information from 3 acute oral toxicity tests in rats (2/group) fed dietary doses of 1.0, 1.26 1.58, or 2.0 g/kg led to mortality at 1.26 g/kg and above, and initial weight loss and slight retrograde degeneration of the kidney was seen in 1.58 and 2.0 mg/kg groups. No observable effects were noted at 1.0 g/kg. Summary reports of 3 eye irritation studies in rabbits indicate that 1% TMBP in propylene glycol administered to unwashed or washed eyes is slightly irritating and painful. Instillation of 10% and 100%concentrations showed increasing severity of effects, including corneal burns. Summary reports of primary skin irritation tests in rabbits indicate treatment-related irritation occurs with exposure to 1%, 10%, and 100% TMBP in 50B (not described). |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802980 |
| Origin |
NTIS |
| Type |
CAT |
