Main Title |
Fetotoxic Effects of Nickel in Drinking Water in Mice. |
Author |
Berman, Ezra ;
Rehnberg, Blair ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div. |
Year Published |
1983 |
Report Number |
EPA-600/1-83-007; |
Stock Number |
PB83-225383 |
Additional Subjects |
Nickel chloride ;
Toxicology ;
Pregnancy ;
Dosage ;
Concentration(Composition) ;
Fetotoxity ;
Drinking water
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-225383 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
18p |
Abstract |
Nickel chloride was administered in drinking water to pregnant mice from the 2nd through the 17th day of gestation at nickel doses of 0, 500, or 1000 ppm. Fetal or maternal toxicity was not seen after administration of 500 ppm of nickel. However, the higher dose caused spontaneous abortions, loss of fetal mass in survivors, and loss of maternal mass. The oral route of administration via drinking water was at least 2.7 times less effective than parenteral routes in producing fetal effects. |
PUB Date Free Form |
Jun 83 |
Category Codes |
6T; 57Y |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
328719711 |
Origin |
NTIS |
Type |
CAT |