| Main Title |
Survival of the Fattest: Implications for Acute Effects of Lipophilic Chemicals on Aquatic Populations. |
| Author |
Lassiter, R. R. ;
Hallam., T. G. ;
|
| CORP Author |
Environmental Research Lab., Athens, GA. ;Tennessee Univ., Knoxville. |
| Publisher |
c1990 |
| Year Published |
1990 |
| Report Number |
EPA/600/J-90/153; |
| Stock Number |
PB91-109918 |
| Additional Subjects |
Lipids ;
Mathematical models ;
Toxicology ;
Exposure ;
Bioassays ;
Fats ;
Fishes ;
Reprints ;
Toxic substances ;
Water pollution effects(Animals) ;
Aquatic ecosystems ;
Biological effects ;
Population dynamics ;
Dose-response relationships
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB91-109918 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
Simple assumptions for individual toxic response, exchange of toxicant with environmental concentrations and body composition are used in a model to evaluate the effect of lipid variation on toxic response in a subpopulation of similarly sized individuals. The model represents the internal distribution of a chemical such that more hydrophobic compounds preferentially move into body lipid. Thus, for exposures of equal chemical activity, both increasing body fat and greater hydrophobicities increase the exposure duration that can be withstood without effect. In simulated 96-h bioassays, the effect of increased tolerance to higher hydrophobicities was apparent for chemicals whose K(sub ow) exceeded 10,000. These simulations are compared to published observations. Simulations also are compared to other published data for longer-term bioassays. The effect of interspecies gill morphology on toxic response also is explored. It is concluded that variation in lipid can account for much variation in tolerance in a subpopulation of similarly sized individuals; that gill morphology is another variable influencing toxic response; and that, in general, for similarly exposed organisms, the fattest survives the longest. |
| Supplementary Notes |
Pub. in Environmental Toxicology and Chemistry, v9 p585-595 1990. Presented at the Annual Meeting of the Society of Environmental Toxicology and Chemistry (8th), Pensacola, FL., November 9-12, 1987. Prepared in cooperation with Tennessee Univ., Knoxville. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Survival of the Fattest: Implications for Acute Effects of Lipophilic Chemicals on Aquatic Populations. |
| Category Codes |
68D; 57H; 57Z; 57Y |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
036519428 |
| Origin |
NTIS |
| Type |
CAT |
