| Main Title |
Use of the Spiral Salmonella Assay to Detect the Mutagenicity of Complex Environmental Mixtures. |
| Author |
Houk, V. S. ;
Early, G. ;
Claxton, L. D. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Saint Augustine's College, Raleigh, NC. |
| Publisher |
c1991 |
| Year Published |
1991 |
| Report Number |
EPA/600/J-91/059; |
| Stock Number |
PB91-191668 |
| Additional Subjects |
Mutagenicity tests ;
Environmental pollutants ;
Salmonella typhimurium ;
Mixtures ;
Exhaust emissions ;
Solvents ;
Metabolic activation ;
Diesel fuels ;
Reprints ;
Wood smoke ;
Coal combustion emissions
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB91-191668 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Three sets of combustion emissions were selected for evaluation: automotive diesel exhaust, woodsmoke, and a coal combustion emission. Each sample was tested in the Salmonella mutagenicity assay according to standard protocol (plate incorporation) and spiral assay techniques. Two assays demonstrated the following: (1) Diesel exhaust was generally the most mutagenically potent sample in both assays. (2) Samples were more mutagenic on rev/microgram basis in the spiral assay, especially when metabolic activation was added. (3) The spiral assay required 1/20 the sample mass of the standard assay to test equivalent doses. (4) Dichloromethane extracts of the complex mixtures could be tested for mutagenicity in the spiral assay. |
| Supplementary Notes |
Pub. in Environmental and Molecular Mutagenesis, v17 p112-121 Mar 91. Prepared in cooperation with Saint Augustine's College, Raleigh, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Use of the Spiral Salmonella Assay to Detect the Mutagenicity of Complex Environmental Mixtures. |
| Category Codes |
68G; 57Y; 57F |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
119326407 |
| Origin |
NTIS |
| Type |
CAT |
