| Main Title |
Toxicity testing for assessment of environmental agents : interim report / |
| Publisher |
National Academies Press, |
| Year Published |
2006 |
| OCLC Number |
62793577 |
| ISBN |
9780309100922; 0309100925; 9780309656528; 0309656524 |
| Subjects |
Toxicity testing ;
Toxicology ;
Environmental Pollutants--toxicity ;
Toxicity Tests
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EIAM |
QH541.15.T68T68 2006 |
|
Region 2 Library/New York,NY |
04/14/2006 |
| EJBM |
QH541.15.T68T68 2006 |
|
Headquarters Library/Washington,DC |
04/21/2006 |
| EJEM |
QH541.15.T68T68 2006 |
|
OCSPP Chemical Library/Washington,DC |
04/28/2006 |
| EKBM |
QH541.15.T68T685 2006 |
|
Research Triangle Park Library/RTP, NC |
03/23/2009 |
| EOAM |
QH541.15.T68T68 2006 |
|
Region 8 Technical Library/Denver,CO |
05/05/2006 |
|
| Edition |
Prepublication copy. |
| Collation |
xxiii, 244 pages : illustrations ; 23 cm |
| Notes |
Includes bibliographical references. |
| Contents Notes |
Preface -- Abbreviations -- Summary -- 1: Introduction -- Regulatory Requirements -- Toxicity Testing -- Challenges to Toxicity Testing and Assessment -- Committee's Task and Approach -- Organization of the Report -- References -- 2: Animal and In Vitro Toxicity Testing -- Toxicity Testing Characterized by Exposure Duration -- Toxicity Testing Characterized by Specific End Point -- Mechanistic Testing: Metabolism and Pharmacokinetic Studies -- References -- 3: Human Data -- Clinical or Controlled-Exposure Studies -- Case Reports -- Epidemiologic Studies -- Use of Human Data for Regulatory Analyses -- Challenges to the Advancement of Epidemiology -- Contributions of Emerging Fields to Epidemiology -- References -- 4: Strategies for Toxicity Testing -- Types of Toxicity-Testing Strategies -- Toxicity-Testing Strategies for Pesticides and Food Additives -- Toxicity-Testing Strategies for Screening of Industrial Chemicals -- Strategies for Screening Chemicals for Effects on Specific Systems and End Points -- Committee Observations on Toxicity-Testing Strategies -- References -- 5: Use of Data in Human Health Risk Assessment -- Noncancer Risk-Assessment Guidance -- Cancer Risk-Assessment Guidance -- Committee Observations Concerning Toxicity Data Available for Risk Assessment -- References -- 6: New Approaches -- Approaches for Improving Existing Toxicity-Testing Strategies -- Committee Evaluation of Suggested Improvements in Testing Strategies -- References -- 7: Alternative Approaches and Emerging Technologies -- Alternatives to Current Animal-Testing Approaches -- Emerging Technologies -- Validation -- References -- APPENDIXES -- Appendix A Biographic Information on the Committee on Toxicity Testing and Assessment of Environmental Agents. |
| Place Published |
Washington, D.C. |
| Access Notes |
Also available online.; Mode of access: World Wide Web.; System requirements: Adobe Acrobat Reader. |
| Corporate Au Added Ent |
National Research Council (U.S.). Committee on Toxicity Testing and Assessment of Environmental Agents. |
| PUB Date Free Form |
c2006 |
| BIB Level |
m |
| Medium |
electronic resource |
| Cataloging Source |
OCLC/T |
| LCCN |
2006923288 |
| Merged OCLC records |
66904719; 70294691; 224715208; 551620631; 977386332; 1013260905 |
| OCLC Time Stamp |
20090316120756 |
| Language |
eng |
| Origin |
OCLC |
| Type |
CAT |
| OCLC Rec Leader |
02122cam 22005414a 45020 |
