Main Title |
Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases [electronic resource] / |
Type |
EBOOK |
Other Authors |
|
Publisher |
Springer International Publishing : Imprint: Springer, |
Year Published |
2015 |
Call Number |
QP356.3 |
ISBN |
9783319183657 |
Subjects |
Medicine ;
Neurochemistry ;
Nutrition ;
Pharmacy ;
Neurology
|
Internet Access |
|
Collation |
VII, 163 p. 41 illus., 26 illus. in color. online resource. |
Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
Contents Notes |
Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer's disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson's disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry. |
Place Published |
Cham |
Corporate Au Added Ent |
SpringerLink (Online service) |
Title Ser Add Ent |
Advances in Experimental Medicine and Biology, 863 |
Host Item Entry |
Springer eBooks |
PUB Date Free Form |
2015 |
Series Title Untraced |
Advances in Experimental Medicine and Biology, 863 |
BIB Level |
m |
Medium |
computer |
Content |
text |
Carrier |
online resource |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20150621023710 |
Language |
eng |
Origin |
SPRINGER |
Type |
EBOOK |
OCLC Rec Leader |
03808nam a22004935i 45 |