| Main Title |
Disposition of (2-hexyl 14c) Di-(2-ethylhexyl) Phthalate in the Rat with Cover Letter dated 09/17/1984. |
| CORP Author |
Raltech Scientific Services, Inc., Madison, WI.; Hooker Chemical Corp., Burlington, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1984 |
| Report Number |
40-8426136 |
| Stock Number |
OTS0508495 |
| Additional Subjects |
Toxicology ;
Health effects ;
Benzylbutyl Phthalate ;
Pharmaco Kinetics ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 117-81-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0508495 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
87p |
| Abstract |
The absorption, distribution and elimination of (2-hexyl 14C) di(2-ethylhexyl)phthalate (14C-DEHP) was studied in four male Sprague-Dawley rats administered 14C-DEHP by gavage at a nominal dose of 100 mg/kg of body weight. 61.5% of the radioactivity was recovered in the feces, of which 34% and 4% were unchanged DEHP and MEHP respectively. The remainder (29.9%) was eliminated in the urine in the form of metabolites and expired air as 14CO2 (3.7%). The excretion of expired 14CO2 was biphasic with an alpha-phase half-life of 3.1 hrs and a beta-phase half-life of 41.1 hrs. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Hooker Chemical Corp., Burlington, NJ. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1984 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A06/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801310 |
| Origin |
NTIS |
| Type |
CAT |
