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Main Title Ames Test Curve Fitting Program. A User's Guide.
Author Hasselbald, Vic ; Stead, Andy ; Creason, John ; Kasica, Violette ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1980
Report Number EPA-600/2-80-184;
Stock Number PB81-156267
Additional Subjects Curve fitting ; Computer programs ; Statistical analysis ; Programming manuals ; Fortran ; Maximum likelihood estimation ; UNIVAC-1110 computers ; Parameter estimation ; Goodness of fit tests ; Likelihood ratio tests
Library Call Number Additional Info Location Last
NTIS  PB81-156267 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 60p
Abstract The Ames Test Curve Fitting program is a Fortran program which fits a nonlinear dose-response curve to count (Poisson) data. The program was written specifically for analyzing Ames test data, although it is possible that the program could have other applications. The curve fitted is of the form (a+exp(b+clogX)exp(-dx)) where a, b, c and d are parameters to be estimated. If the parameter d is very near zero, then d is dropped from the model, and a reduced model is fitted. Tests of goodness-of-fit and for the significance of the parameters are made using likelihood ratio tests. The program has optional graphics capability for producing plots of the data and the estimated curve.
PUB Date Free Form Sep 80
Category Codes 9B; 12A; 62B; 72F
NTIS Prices PC A04/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 323792115
Origin NTIS
Type CAT