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RECORD NUMBER: 675 OF 2539

Main Title Dosimetry of Ozone and Nitrogen Dioxide in Man and Animals.
Author Overton, Jr., J. H. ; Miller, F. J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Northrop Services, Inc., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-600/D-84-126;
Stock Number PB84-195304
Additional Subjects Ozone ; Nitrogen dioxide ; Dosimetry ; Toxicology ; Air pollution ; Exposure ; Absorption ; Mathematical models ; Extrapolation ; Standards ; Dosage ; Forecasting ; Public health ; Laboratory animals ; Air pollution effects(Humans) ; Air pollution effects(Animals) ; Toxic substances ; National ambient air quality standards
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Library Call Number Additional Info Location Last
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Status
NTIS  PB84-195304 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 15p
Abstract Agreement between experimental data on maximum morphological damage and maximal predicated tissue does offers promise that mathematical dosimetry models can contribute to a better understanding of effective doses in animal studies and their correspondence to human exposure levels. Modeling must be a dynamic process to take advantage of new information and evolving conceptualizations of physical, chemical, and biological processes. Qualitative extrapolations from animals to man have been indirectly in setting National Ambient Air Quality Standards. Continued development of dosimetry models, along with information on species differences in sensitivity to pollutants, have the potential to make extrapolations between animals and man more quantitative in the future.
Supplementary Notes Prepared in cooperation with Northrop Services, Inc., Research Triangle Park, NC.
PUB Date Free Form May 84
Category Codes 6T; 6E; 68G; 68A; 57Y; 57U
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 423019815
Origin NTIS
Type CAT