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OLS Field Name OLS Field Data
Main Title Toxicity of Chlorine Dioxide in Drinking Water.
Author Abdel-Rahman, M. S. ; Couri, D. ; Bull, R. J. ;
CORP Author New Jersey Medical School, Newark. Dept. of Pharmacology. ;Ohio State Univ., Columbus. Coll. of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA-R-807473; EPA/600/J-84/175;
Stock Number PB85-146736
Additional Subjects Chlorine oxides ; Toxicity ; Water treatment ; Disinfection ; Rodents ; Blood cells ; Liver ; Kidney ; Weight(Mass) ; Intestines ; Reprints ; Chlorine dioxide ; Drinking water
Library Call Number Additional Info Location Last
NTIS  PB85-146736 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 10p
Abstract Chlorine dioxide (ClO2) is currently being considered as an alternate to chlorine as a disinfectant for public water supplies. Studies were conducted to determine the toxicity of ClO2 (0, 1, 10, 100, 1000 mg/L) and its metabolites, ClO2(-1) and ClO3(-1) (10, 100 mg/L) in drinking water in rats. After 9 months treatment the osmotic fragility of the red blood cells was decreased in all treatment groups, while a decreased blood glutathione was only observed in the metabolite groups. At 2, 4, and 6 months no significant hematologic changes were noted in treated rats compared to control. However, after 9 months RBC counts, hematocrit, and hemoglobin were decreased in all treatment groups. ClO2, ClO2(-1), and ClO3(-1) administered chronically in drinking water for 3 months inhibited the incorporation of (3)H-thymidine into nuclei of rat tests. The treatment with Cl compounds decreased rat body weight in all groups after 10 and 11 months treatment.
Supplementary Notes Prepared in cooperation with Ohio State Univ., Columbus. Coll. of Medicine.
Availability Notes Pub. in Jnl. of the American College of Toxicology, v3 n4 p277-284 1984.
NTIS Title Notes Journal article.
Title Annotations Reprint: Toxicity of Chlorine Dioxide in Drinking Water.
PUB Date Free Form c1984
Category Codes 13B; 6T; 6C; 50B; 57Y; 57Z
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 510224035
Origin NTIS
Type CAT