| Main Title |
Fornix Transections Disrupt the Ontogeny of Latent Inhibition in the Rat. |
| Author |
Nicolle, M. M. ;
Barry, C. C. ;
Veronesi, B. ;
Stanton, M. E. ;
|
| CORP Author |
Environmental Protection Agency, Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill. ;NSI Technology Services Corp., Research Triangle Park, NC. |
| Publisher |
c1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-89/338; |
| Stock Number |
PB90-201682 |
| Additional Subjects |
Animal behavior ;
Hippocampus ;
Acetylcholinesterase ;
Graphs(Charts) ;
Reprints ;
Ontogeny ;
Taste aversion ;
Latent inhibition ;
Immunohistochemistry ;
Weaning
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-201682 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
In three experiments, the study examined the ontogeny of latent inhibition in a conditioned taste aversion paradigm. In the first experiment, 18-, 25-, and 32-day-old rats received a pairing of a 0.6% Sanka solution with a LiCl injection (.75% BW, .4M) or physiologically balanced saline injection after either 4 preexposures to the taste or control treatment without taste preexposure. Experiment 2 investigated the possibility that a failure to observe latent inhibition in 18-day-old resulted from the particular experimental parameters employed in Experiment 1. In Experiment 2, taste exposure durations were longer, the retention interval between conditioning and testing was shorter, and deprivation conditions were more typical of those used with preweanling subjects. In Experiment 3, the study examined the effect of sham or fornix lesions at 18 days of age on latent inhibition at 32 days of age. Lesioned subjects exhibited equivalent conditioned taste aversions but failed to show latent inhibition. |
| Supplementary Notes |
Pub. in Psychobiology, v17 p349-357 1989. Prepared in cooperation with North Carolina Univ. at Chapel Hill, and NSI Technology Services Corp., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Fornix Transections Disrupt the Ontogeny of Latent Inhibition in the Rat. |
| Category Codes |
57Z; 57S; 57B |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
016616903 |
| Origin |
NTIS |
| Type |
CAT |
