| Main Title |
Effects of 0.1 ppm Nitrogen Dioxide on Airways of Normal and Asthmatic Subjects. |
| Author |
Hazucha, Milan J. ;
Ginsberg, Joel F. ;
McDonnell, William F. ;
Haak, Jr., Edward D. ;
Pimmel, Russell L. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ., Chapel Hill. |
| Year Published |
1983 |
| Report Number |
EPA-600/J-82-021; |
| Stock Number |
PB83-223701 |
| Additional Subjects |
Nitrogen dioxide ;
Toxicology ;
Respiratory system ;
Asthma ;
Exposure ;
Physiological effects ;
Reprints ;
Air pollution effects(Humans)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-223701 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
It has been reported that inhalation of nitrogen dioxide (NO2) will enhance the bronchial reactivity of asthmatics. This study was designed to evaluate the respiratory effect of a 1-h exposure of normal subjects and of atopic asthmatics to 0.1 parts per million (ppm) NO2. Fifteen normal and 15 asthmatic subjects were exposed to air and to NO2 in randomized double-blind crossover design. Exposure to either atmosphere was bracketed by bronchial inhalation challenge using aerosolized metacholine chloride solutions. Plethysmographic measurements of specific airway resistance (sRaw) and the forced random noise impedance spectrum (5-30 Hz) were obtained immediately after each methacholine dose. |
| Supplementary Notes |
Pub. in Jnl. of Applied Physiol Respirat Environ Exercise, p730-739 1983. Prepared in cooperation with North Carolina Univ., Chapel Hill. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Effects of 0.1 ppm Nitrogen Dioxide on Airways of Normal and Asthmatic Subjects. |
| PUB Date Free Form |
1983 |
| Category Codes |
6T; 6F; 57Y; 68D |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
321722285 |
| Origin |
NTIS |
| Type |
CAT |
