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Main Title Behavioral Effects of Acute p-Xylene Inhalation in Rats: Autoshaping, Motor Activity, and Reversal Learning.
Author Bushnell, P. J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher 1988
Year Published 1988
Report Number EPA/600/J-89/017;
Stock Number PB89-236293
Additional Subjects Xylenes ; Cognition ; Learning ; Animal behavior ; Rats ; Reaction time ; Exposure ; Dosage ; Reprints ; Air pollution effects(Animals) ; Neurophysiology
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NTIS  PB89-236293 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
Abstract To evaluate the possibility that p-xylene affects cognitive behavior, young adult male Long-Evans hooded rats inhaled p-xylene at concentrations of 0 or 1600 ppm, 4 hr per day for 1 to 5 days, and were evaluated after exposure on two learning tasks and a test of motor activity. Autoshaping was carried out across 5 successive days with p-xylene exposure in the morning followed by testing in the afternoon. The results were interpreted to indicate that p-xylene inhalation at 16 times the TLV induced hyperactivity and facilitated autoshaping by different means, and that the facilitation of autoshaping was not a directed effect on learning per se.
Supplementary Notes Pub. in Neurotoxicology and Teratology, v10 n6 p569-577, 1989. Presented at the Society for Neuroscience Annual Meeting, New Orleans, LA., November 18, 1987.
NTIS Title Notes Journal article.
Title Annotations Reprint: Behavioral Effects of Acute p-Xylene Inhalation in Rats: Autoshaping, Motor Activity, and Reversal Learning.
Category Codes 68A; 57Y; 92B
NTIS Prices PC A03/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 931317601
Origin NTIS
Type CAT