| Main Title |
Letter from Eastman Kodak Company to US EPA regarding Information on 5-Methyl-2-Octanone 90-Day Feeding Study. |
| CORP Author |
Tennessee Eastman Co., Kingsport.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
21 Feb 1979 |
| Year Published |
1979 |
| Report Number |
8EHQ-0279-0275; |
| Stock Number |
OTS-0200457 |
| Additional Subjects |
Toxicity ;
Solvents ;
Rats ;
Gavage ;
Laboratory tests ;
Central nervous system ;
Neuropathy ;
Dosage ;
Feeding ;
US EPA ;
Alkanes ;
Ketones ;
In vivo analysis ;
Neurotoxins ;
Metabolism ;
Adverse effects ;
MHK solvent ;
5-methyl-2-octanone ;
Eastman Kodak Company
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200457 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
9p |
| Abstract |
The submission reports that chronic administration of MHK Solvent (5-methyl-2-octanone; 72% minimum) to rats by gavage over a 90-day period induced signs of hind-limb weakness in several of the test animals. Histologic examination of peripheral and central nervous system sections revealed giant axonal neuropathy in the MHK Solvent-dosed rats. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y; 57S; 68G |
| NTIS Prices |
PC A02/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
035500930 |
| Origin |
NTIS |
| Type |
CAT |
