| Main Title |
Evaluation of Sensory System Function Using Reflex Modification of the Startle Response. |
| Author |
Crofton, K. M. ;
Sheets., L. P. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-89/445; |
| Stock Number |
PB91-109371 |
| Additional Subjects |
Public health ;
Chemical compounds ;
Environmental surveys ;
Senses ;
Exposure ;
Toxicology ;
Reflexes ;
Nervous system disorders ;
Reprints ;
Toxic substances ;
Startle raction
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB91-109371 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
15p |
| Abstract |
Methods to measure damage to sensory systems following toxicant exposure vary from rapid and subjective tests (e.g., pinna reflex) to time-consuming and objective tests (e.g., psychophysical tests). Reflex modification of the startle response represents an alternative technique in the assessment of sensory function. Advantages of this procedure include: no prior training requirements, rapid and objective measurement of sensory thresholds, ability to differentiate sensory from non-sensory damage, and potential for predictive validity. This procedure has also been shown to be sensitive to a variety of neurotoxic compounds. Future research should concentrate on demonstrating the research potential of this technique for use in neurotoxicology. |
| Supplementary Notes |
Pub. in Jnl. of the American College of Toxicology, v8 n1 p199-211 Mar 89. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Evaluation of Sensory System Function Using Reflex Modification of the Startle Response. |
| Category Codes |
68G; 57U; 57S; 57Y |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
036519204 |
| Origin |
NTIS |
| Type |
CAT |
