Main Title |
Electrophysiological and Morphological Evidence for a Diameter-Based Innervation Pattern of the Superior Colliculus (Journal Version). |
Author |
Boyes, W. K. ;
Veronesi, B. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. |
Publisher |
1988 |
Year Published |
1988 |
Report Number |
EPA/600/J-88/151; |
Stock Number |
PB89-109243 |
Additional Subjects |
Optic nerve ;
Superior colliculus ;
Neural transmission ;
Electrophysiology ;
Nerve fibers ;
Optic chiasm ;
Laboratory animals ;
Morphology ;
Electron microscopy ;
Axons ;
Reprints ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-109243 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
20p |
Abstract |
Neurophysiological and morphological techniques were used to describe changes in the optic tract and superior colliculus (SC) in response to monocular enucleation. Long-Evans, male, (250g) rats were implanted with chronic bipolar stimulating electrodes located in the optic chiasm and a recording electrode located below the stratum griseum superficiale (SGS) and referenced to a skull screw electrode. In rats with satisfactory electrode placements (n=17), peaks corresponding to rapidly conducting presynaptic activity (Pre), rapidly conducting postsynaptic activity (Nl), and slowly conducting postsynaptic activity (P3), were identified according to peak latency, polarity, stimulation threshold, and resistance to 100 Hz stimulation. These peaks diminished differentially over a seven day (D1-7) post-enucleation period. Those peaks reflecting rapidly conducting axons (i.e., Pre, N1) decayed by D2, whereas those reflecting slowly conducting axons (i.e., P3) persisted until D4 and completely decayed by D7. |
Supplementary Notes |
Pub. in Experimental Neurology, v101 p190-207 1988. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Electrophysiological and Morphological Evidence for a Diameter-Based Innervation Pattern of the Superior Colliculus (Journal Version). |
Category Codes |
57I; 57A; 57S |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
834423877 |
Origin |
NTIS |
Type |
CAT |