| Main Title |
Review of Jorgenson/SRI Tumor Incidence Data for Rats and Mice Exposed to Chloroform in Drinking Water Implications for Chloroform Risk Assessment. |
| Author |
Chiu, A. ;
Ris, C. ;
Singh, D. ;
|
| CORP Author |
Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment. |
| Publisher |
Apr 96 |
| Year Published |
1996 |
| Report Number |
EPA/600/R-96/035 ;NCEA-W-0079; |
| Stock Number |
PB96-169909 |
| Additional Subjects |
Chloroform ;
Drinking water ;
Toxicity ;
Risk assessment ;
Mice ;
Rats ;
Bioassay ;
Neoplasms ;
Carcinogenesis ;
Dose-response relationships ;
Exposure ;
Mortality ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB96-169909 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
45p |
| Abstract |
The purpose of the review was to revisit a mouse and rat bioassay for chloroform in drinking water done under contract for EPA and reported in the literature by Jorgenson et al, in 1985. The review had several objectives including to reconcile apparently different records of tumor counts, to elucidate additional tumor occurences that were reported but not discussed in detail, and to consider anaimal-at-risk counts that would be important for quantitative risk analysis. These topics are viewed as important considerations because EPA's present chloroform cancer risk characterization depends heavily on this bioassay; yet, the detained bioassay reports have never been scrutinized. |
| Category Codes |
68D; 57Y; 57S |
| NTIS Prices |
PC A04/MF A01 |
| Primary Description |
600/21 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
622000800 |
| Origin |
NTIS |
| Type |
CAT |
