Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 412 OF 1140

Main Title Evaluation of the Dermal Carcinogenic Potential of Pentaerythritol Acrylate-HF with Attachments and Cover Letter dated 07/28/88.
CORP Author Union Carbide Corp., Danbury, CT. ;Carnegie-Mellon Inst. of Research, Pittsburgh, PA.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 2 Aug 1988
Year Published 1988
Report Number FYI-OTS-0888-0629;
Stock Number OTS-0000629
Additional Subjects Carcinogens ; Dermal absorption ; Toxicity ; Chemical hygine ; Malignant neoplasms ; Tumors ; Pentaerythritol aerylate-HF ; Union Carbide Corporation(Trademark) ; 511-01-6656 ; 16-CHC-111-3
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  OTS-0000629 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Abstract Forty C3H/HeJ male mice were painted 3 times per week for their lifespan on the skin of the back, clipped free of fur, with pentaerythritol acrylate-HF as a 15% dilution in acetone at an average dose of 0.0026 grass pentaerythritol acrylate-HF/mouse/application. A negative control group of 40 C3H/HeJ male mice received repeated skin paintings of undiluted acetone at an average dose of 0.012 grams/mouse/application. No skin tumors were observed in the group of mice painted with pentaerythritol acrylate-HF. One mouse in the group painted with acetone had a histologically verified squamous cell carcinoma of the skin near the right eye which may or may not have been due to treatment.
Supplementary Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC.
Availability Notes Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA.
Category Codes 57Y; 99
NTIS Prices PC A03/MF$25.00
Document Type NT
Cataloging Source NTIS/MT
Control Number 019102940
Origin NTIS
Type CAT