Main Title |
Effect of Cigarette Smoking in Epidemiological Studies of Lung Cancer. |
Author |
Whittemore, A. S. ;
|
CORP Author |
Stanford Univ., CA. Dept. of Family, Community and Preventive Medicine.;Health Effects Research Lab., Research Triangle Park, NC. |
Publisher |
c1988 |
Year Published |
1988 |
Report Number |
EPA-R-813495; EPA/600/J-88/519; |
Stock Number |
PB90-232174 |
Additional Subjects |
Smoking ;
Epidemiology ;
Statistical analysis ;
Regression analysis ;
Reprints ;
Lung neoplasms ;
Goodness of fit
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB90-232174 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
18p |
Abstract |
The paper describes a method for adjusting the analysis of occupational/environmental lung cancer risks for the effects of cigarette smoking in cohort and case-control studies. The method uses a function that relates an individual's death rate to his age and cigarette smoking history. Two such functions are examined. The first depends on total packs of cigarettes smoked and age. The second, based on the multistage theory of carcinogenesis, depends on age, age at start of smoking, and subsequent smoking rates. The lung cancer rates predicted by these two functions are compared to those observed in cohort studies of male British physicians and U.S. veterans, and in a case-control study of non-Hispanic white men in New Mexico. Neither of the cohort data sets distinguished the fit of the two functions. The New Mexico data were fit better by the second function, though both functions overpredicted death rates among ex-smokers. Each function explained substantially more variation in the New Mexico data than did any of several logistic regression models involving categorical variables for age and smoking. (Copyright (c) 1988 by John Wiley & Sons, Ltd.) |
Supplementary Notes |
Pub. in Statistics in Medicine, v7 p223-238 Feb 88. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Effect of Cigarette Smoking in Epidemiological Studies of Lung Cancer. |
Category Codes |
57U; 57E; 72F |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/10 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
022221141 |
Origin |
NTIS |
Type |
CAT |