| Main Title |
Alteration of Cellular Interactions in the Immune System: Natural Killer Activity and N Lymphocytes. |
| Author |
Burleson, G. R. ;
|
| CORP Author |
Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1987 |
| Report Number |
EPA-68-02-4450; EPA/600/D-87/302; |
| Stock Number |
PB88-106414 |
| Additional Subjects |
Immunology ;
Neoplasms ;
Viral diseases ;
Lymphocytes ;
Killer cells(Natural) ;
Immune system ;
Suppressor cells ;
NK(Natural killer)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-106414 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
56p |
| Abstract |
N lymphocytes, like interferons, have three major biological functions: (1) antitumor activity; (2) antiviral activity; and (3) immunoregulatory activity. Antitumor activity is also referred to as natural killer (NK) activity which represents the non-MHC-restricted lysis of NK-sensitive tumor cells by effector cells obtained from a nonimmunized host. N lymphocytes play a pivotal role in a network of immune functions. The review discusses the (1) properties of natural killer activity, (2) importance of natural killer activity against tumor cells, (3) importance of N lymphocytes in viral infections, (4) regulation of natural killer activity by cytokines, (5) alteration of natural killer activity by suppressor cells, and (6) alteration of natural killer activity by chemicals. |
| Supplementary Notes |
Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| PUB Date Free Form |
Sep 87 |
| Category Codes |
57J; 57E |
| NTIS Prices |
PC A04/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
735120872 |
| Origin |
NTIS |
| Type |
CAT |
