Main Title |
Alpha-Olefin Epoxide C-16 Salmonella/Microsome (Ames) Bacterial Mutagenicity Assay with Cover Letter. |
CORP Author |
Union Carbide Corp., Oak Ridge, TN. Office of Health, Safety, and Environmental Affairs.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1984 |
Report Number |
878214505 |
Stock Number |
OTS-0206602 |
Additional Subjects |
Toxicity ;
Mutagenicity assays ;
Genotoxicity ;
Cells (Biology) ;
Gene mutations ;
Health effects ;
Bacteria ;
In vitro ;
Concentrations ;
Metabolic activation ;
Liver cells ;
Alkyl epoxides ;
Alpha-o1efin epoxide C-16 ;
Ames Test ;
CAS No 7320-37-8 ;
Salmonella typhimurium ;
Union Carbide Corporation
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS-0206602 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
48p |
Abstract |
Alpha-o1efin epoxide C-16 was tested for potential mutagenic activity using the Salmonella/microsome bacterial mutagenicity assay (Ames test). alpha-olefin epoxide C-16 was tested in triplicate at five concentrations, ranging from 0.1 allligram to 10 milligrams per plate. The highest concentration was cytotoxic in the mutagenicity test and in a preliminary test to choose appropriate doses. Mutagenic activity was not observed with any of the five bacterial strains tested with or without metabolic activation. alpha-olefin epoxide C-16 was not mutagenic in this screening test. |
Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
PUB Date Free Form |
25 Jul 1984 |
Category Codes |
57Y; 57F; 57K |
NTIS Prices |
PC A04/MF A04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
019001730 |
Origin |
NTIS |
Type |
CAT |