| Main Title |
Kronitex Tbp (tributyl Phosphate) Mutagenicity Screening Test Salmonella Microsomal Assay (ames Test) with Cover Letter dated 08/08/1986. |
| CORP Author |
FMC Corp., Philadelphia, PA.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1986 |
| Report Number |
86860000112 |
| Stock Number |
OTS0510260 |
| Additional Subjects |
Toxicology ;
Health effects ;
Phosphoric Acid Tributyl Ester (126-73-8) ;
Genotoxicity ;
Gene Mutations ;
Bacteria ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 126-73-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0510260 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
25p |
| Abstract |
The mutagenicity of tri-n-butyl phosphate was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537 and TA1538 (Ames Test), both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Tri-n-butyl phosphate, diluted with DMSO, was tested at concentrations up to 100ul/plate using the plate incorporation technique. Tri-n-butyl phosphate did not produce a positive response in any tester strain with metabolic activation. Tester strains TA1535, TA1537 and TA1538 without metabolic activation, produced twice the number of revertants/plate compared to the solvent control (DMSO) for at least three of the five test concentrations, but a dose-response was not observed. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1986 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801390 |
| Origin |
NTIS |
| Type |
CAT |
