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OLS Field Name OLS Field Data
Main Title Toxic effects of xenobiotics on the pituitary gland. {microfiche}
Author Walker, R.F. ; Cooper., R. L.
CORP Author Smith Kline Beecham Corp., King of Prussia, PA. Dept. of Toxicology.;Health Effects Research Lab., Research Triangle Park, NC. Toxicology Branch.
Publisher Smith Kline Beecham for US Environmental Protection Agency,
Year Published 1991
Report Number EPA/600/D-90/198
Stock Number PB91-136903
Additional Subjects Toxicity ; Pituitary gland ; Metals ; Reproduction(Biology) ; Homeostasis ; Estrogen ; Pesticides ; Hypothalamus ; Pituitary neoplasms ; Xenobiotics ; Toxic substances ; Monoamines ; Carcinogenicity tests
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB91-136903 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 55 p. ; 28 cm.
Abstract The document provides a summary of adverse effects of xenobiotics upon the pituitary gland, an endocrine gland that plays an important role in the regulation of reproductive function. The most common histopathological pituitary lesions observed following exposure to drugs and chemicals are reviewed along with the potential consequences of these lesions on physiological function and the maintenance of homeostasis. In addition, other mechanisms involved in the alteration of pituitary function are discussed. These include changes in function that occur in response to a toxicant's effect on the central nervous system or target gland and thus indirectly influence pituitary gland activity.
Notes "EPA 600/D-90/198."
Place Published King of Prussia, PA.,
Supplementary Notes Sponsored by Health Effects Research Lab., Research Triangle Park, NC. Toxicology Branch.
PUB Date Free Form 1990.
NTIS Prices PC A04/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20001226185637
Language eng
Origin NTIS
Type MERGE
OCLC Rec Leader 00757nam 2200205Ka 45020