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RECORD NUMBER: 110 OF 249

Main Title Methods to Quantify Endocytosis: A Review.
Author Kavet, R. I. ; Brain, J. D. ;
CORP Author Harvard School of Public Health, Boston, MA. Dept. of Physiology.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1980
Report Number EPA-R-805091; EPA-600/J-80-451;
Stock Number PB84-222678
Additional Subjects Cells(Biology) ; Molecular biology ; Measurement ; In vivo analysis ; In vitro analysis ; Reprints ; Endocytosis
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NTIS  PB84-222678 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 24p
Abstract Endocytosis is a process whereby extracellular matter is transported in bulk to the cell's interior. To accomplish this the cell extends portions of the plasma membrane which surround the mass to be ingested. As these cytoplasmic projections meet, they fuse. The endocytic vacuole thus formed pinches off from the plasma membrane's inner aspect from where it may be transported deeper into the cell. Alternatively such structures may form when a portion of the cell surface invaginates followed by plasma membrane fusion at the mouth of the invagination. In either case, matter which was formerly outside the cell becomes internalized through a complex process which requires a coordinated interaction of the plasma membrane with contractile elements in the cytoplasm. Usually, the ingested matter is subjected to digestive attack. This occurs when the ingested vacuole merges with lysosmes and the contents of each mix. Lysosomes are vesicular bodies containing both digestive enzymes which break down macromolecules, and enzymes that catalyze pathways which mediate killing of certain microbes.
Availability Notes Pub. in Jnl. of the Reticuloendothelial Society, v27 n2 p201-221 Feb 80.
NTIS Title Notes Journal article.
Title Annotations Reprint: Methods to Quantify Endocytosis: A Review.
PUB Date Free Form c1980
Category Codes 6C; 57F
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 430021941
Origin NTIS
Type CAT