| Main Title |
Initial Submission: Chronic Mouse Dermal Toxicity Study of a Mixture of Valeric Acid; Heptanoic Acid; Pelargonic Acid; and Tripropylene Glycol of Hexafluoroisopropanol in Guinea Pigs and Rats with Cover Letter dated 10/15/1992. |
| CORP Author |
Charles F. Kettering Research Lab., Yellow Springs, OH.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-1092-11669 |
| Stock Number |
OTS0571597 |
| Additional Subjects |
Toxicology ;
Health effects ;
Valeric acid ;
Heptanoic acid ;
Pelargonic acid ;
Tripropylene ;
Chronic toxicity ;
Carcinogenicity ;
Mammals ;
Mice ;
Dermal ;
CAS No 109-52-4 ;
CAS No 111-14-8 ;
CAS No 112-05-0 ;
CAS No 42978-66-5
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571597 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
105p |
| Abstract |
Groups of 50 male mice received twice-weekly applications of 25 or 50 mg doses of a test material. C-181 induced four skin tumors in three mice when tested in 50 mg doses as a 75% solution in mineral oil. Both benign and malignant skin tumors were observed in 1750 mice treated with C-180 along with severe dermal and systemic toxicity. An 18% decrease in average body weight and a marked reduction in survival was observed with C-180. No skin tumors were observed with either C- 178 or C-182. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
30 Oct 1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A07/MF A07 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028700690 |
| Origin |
NTIS |
| Type |
CAT |
