| Main Title |
Initial Submission: A Cutaneous Carcinogenicity Study with Mice on the Diglycidyl Ether of 1,4-Butane Diol with Cover Letter dated 10/16/1992. |
| CORP Author |
Shell Toxicology Lab., Tungstall, UK.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-1092-11490 |
| Stock Number |
OTS0571421 |
| Additional Subjects |
Toxicology ;
Health effects ;
Diglycideyl ether of 1 ;
4-butane diol ;
Chronic toxicity ;
Carcinogenicity ;
Mammals ;
Mice ;
Dermal ;
CAS No 2425-79-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571421 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
156p |
| Abstract |
The carcinogenic potential of diglycidyl ether of 1,4-butane diol was assessed in CF1 mice by dermal application of 0.05 and 0.2% w/v in acetone for up to 103 weeks. No statistically significant increase in dermal neoplasms was noted in treated animals. However, females treated with 0.2% were at a higher risk for developing lymphoblastic lymphosarcoma. A similar finding was not seen in males. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
21 Oct 1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A09/MF A09 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028700040 |
| Origin |
NTIS |
| Type |
CAT |
