| Main Title |
Inhalation Teratology Study of T-Dodecyl Mercaptan in Rats and Mice with Cover Letter dated 06/12/86. |
| CORP Author |
International Research and Development Corp., Mattawan, MI. ;Pennwalt Corp., King of Prussia, PA.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
31 Oct 1983 |
| Year Published |
1983 |
| Report Number |
FY-OTS-0686-0234; |
| Stock Number |
OTS-0000234-2 |
| Additional Subjects |
Rats ;
Mice ;
Inhalation ;
Exposure ;
Fetal development ;
Embryo development ;
T-dodercyl mercaptan ;
Teratogenic potential
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000234-2 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Pregnant Charles River CD(trademark)-1 mice and pregnant Charles River COBS(trademark) CD(trademark) rats, randomly assigned to one control group and two t-dodecyl mercaptan treated groups of fifty animals (25 mice and 25 rats) each, were used to determine the teratogenic potential of t-dodecyl mercaptan. Mean actual exposure levels of 22.7 and 88.6 ppm, which correspond to mean nominal exposure levels of 34 and 109 ppm and were designated groups 3 and 4, respectively, were administered by whole body inhalation exposure on gestation days 6 through 16 (mice) or 19 (rats) on a 6-hour daily exposure schedule. The control group was exposed to filtered air only on a comparable regimen. Cesarean sections were performed on all surviving mice on gestation day 17 and on all surviving rats on gestation day 20 and fetuses removed for teratologic evaluation. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y |
| NTIS Prices |
PC A02/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010000070 |
| Origin |
NTIS |
| Type |
CAT |
