| Main Title |
Cytogenetic Distinction between the TK+ and TK- Chromosomes in the L5178Y TK+/- 3.7.2C Mouse-Lymphoma Cell Line. |
| Author |
Hozier, J. ;
Sawyer, J. ;
Clive, D. ;
Moore, M. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Florida Inst. of Tech., Melbourne.;Burroughs Wellcome Co., Research Triangle Park, NC. |
| Year Published |
1982 |
| Report Number |
EPA/600/J-82/462; |
| Stock Number |
PB86-202975 |
| Additional Subjects |
Chromosomes ;
Lymphoma ;
Mice ;
Mutants ;
Reprints ;
Cell lines ;
Cytogenesis ;
Mutagenesis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-202975 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
The authors have analyzed the banded metaphase karyotypes of the L5178Y TK+/-3.72C mouse-lymphoma cell line as well as a class of slow growing (o) TK-/-mutants which show chromosome 11 rearrangements. The authors have discovered a centromeric heteromorphism in the chromosomes 11 (the known location of the thymidine kinase gene in the mouse) which, together with the types of chromosome rearrangements thus far catalogued for TK+/- TK-/- mutagenesis, allows us to propose a cytogenetic distinction between the TK-competent (TK+) and TK-deficient (TK-) chromosome. |
| Supplementary Notes |
Pub. in Mutation Research 105, n6 p451-456 Dec 82. Prepared in cooperation with Florida Inst. of Tech., Melbourne. Sponsored by Burroughs Wellcome Co., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Cytogenetic Distinction between the TK+ and TK- Chromosomes in the L5178Y TK+/- 3.7.2C Mouse-Lymphoma Cell Line. |
| PUB Date Free Form |
c1982 |
| Category Codes |
6C; 57F |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
621323628 |
| Origin |
NTIS |
| Type |
CAT |
