| Main Title |
Compartment Models for Trace Metals in Mammals. |
| Author |
Marcus, A. H. ;
|
| CORP Author |
Washington State Univ., Pullman.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA/600/J-83/344; |
| Stock Number |
PB86-221777 |
| Additional Subjects |
Models ;
Toxicology ;
Metals ;
Exposure ;
Standards ;
Reprints ;
Trace metals ;
Kinetic models
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-221777 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Kinetic models for the distribution and elimination of certain trace metals in mammals allow evaluation of metal burdens in critical target organs under time-variables exposure patterns, and thus may assist in formulating exposure standards. The linear compartmental model is described and some of its implications for conceptual models of trace metal metabolism are developed. The model is then applied to data on multiple doses of cadmium in mice. Many trace metals do not follow simple linear kinetic models because exposure to more than one metal simultaneously often results in synergistic effects. |
| Supplementary Notes |
Pub. in The Science of the Total Environment 28, p307-316 1983. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Compartment Models for Trace Metals in Mammals. |
| PUB Date Free Form |
c1983 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
624115492 |
| Origin |
NTIS |
| Type |
CAT |
