| Main Title |
Toxicity of Fine Chemicals: Preliminary Studies for the Detection of Testicular Changes in Rats with Cover Letter dated 04/25/1986. |
| CORP Author |
Shell Oil Co., Houston, TX.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1986 |
| Report Number |
878216424 |
| Stock Number |
OTS0510352 |
| Additional Subjects |
Toxicology ;
Health effects ;
1 ;
3-dichloropropane (142-28-9) ;
Subchronic Toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Reproduction/fertility Effects ;
Toxic substances ;
Laboratory animals ;
CAS No 96-18-4 ;
CAS No 96-23-1 ;
CAS No 106-95-6 ;
CAS No 109-70-6 ;
CAS No 142-28-9 ;
CAS No 563-47-3 ;
CAS No 627-30-5
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0510352 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
76p |
| Abstract |
3-Bromopropene (CAS No. 106-95-6) was evaluated for subchronic oral toxicity. The test substance was administered by oral gavage to 10 male rats/group for 14 days at 15 mg/kg or 60 mg/kg. Additional groups were exposed to the control vehicles (water or arachis oil) or the positive control, glycerol-a- monochlorohydrin. At 60 mg/kg, signs of compound-related intoxication included excessive salivation in a small number of animals, severe gastric irritation, reduced body weights, and reduced body weight gains. Exposure caused no morphological changes of the reproductive tract and no significant changes in mean testes weights. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1986 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A06/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801520 |
| Origin |
NTIS |
| Type |
CAT |
