| Main Title |
Toxicity of Diphenyl Oxide (Sanitized). |
| CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
86-890001206S |
| Stock Number |
OTS0520718 |
| Additional Subjects |
Toxicology ;
Health effects ;
Diphenyl Oxide (101-84-8) ;
Acute Toxicity ;
Mammals ;
Guinea Pigs ;
Oral ;
Gavage ;
Subchronic Toxicity ;
Primary Dermal Irritation ;
Rabbits ;
Dermal ;
Toxic substances ;
Laboratory animals ;
CAS No 101-84-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0520718 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
3p |
| Abstract |
Summary reports on toxicity tests of diphenyl oxide indicate that 0.2 g/kg bw suspended in 5 - 10% gum acacia solution and administered by gavage to cavies was not lethal, while 1.2 g/kg killed all test animals within 2 weeks post-administration. Nineteen doses of 0.1 g/kg fed (test species not identified) over a period of 29 days caused minor changes (not further described) in one liver lobe. Qualitative experiments involving dermal exposure indicated a single application of test chemical to the ear of the rabbit was non- irritating, while on the abdomen, edema, hyperemia, exfoliation and crustation were evident for 3 to 7 days. Six applications made over a period of 10 days produced exfoliation and necrosis on the ear, and hyperemia, exfoliation, and epithelial hyperplasia on the abdomen. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802150 |
| Origin |
NTIS |
| Type |
CAT |
