| Main Title |
Toxicity of Diphenyl and Diphenyl Oxide (Sanitized). |
| CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
86-890001205S |
| Stock Number |
OTS0520717 |
| Additional Subjects |
Toxicology ;
Health effects ;
Diphenyl Oxide (101-84-8) ;
Acute Toxicity ;
Mammals ;
Rats ;
Oral ;
Subchronic Toxicity ;
Primary Dermal Irritation ;
Rabbits ;
Dermal ;
Guinea Pigs ;
Toxic substances ;
Laboratory animals ;
CAS No 92-52-4 ;
CAS No 101-84-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0520717 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
4p |
| Abstract |
A summary of toxicity tests of diphenyl indicate it is 100% lethal at acute doses of 3 g/kg bw in rats, and repeated doses (20) of 0.1 g/kg was not toxic to the rabbit. A single dermal application of 5% solutions in 95% ethanol and olive oil caused no irritation to rabbit ears and repeated applications (20) to the abdomen caused only a slight reaction. Diphenyl oxide caused 100% lethality to cavies and rats at acute doses of 4.0 g/kg bw. Single dermal application of undiluted diphenyl oxide to rabbit ears produced a slight reaction, while neither 20% nor 5% solutions in olive oil caused irritation. Repeated (20) applicationsof the 20% and 5% olive oil solutions produced a slight reaction. Six applications of undiluted material produced a moderate reaction which healed quickly when treatment was discontinued. One abdominal application of undiluted material produced a moderate reaction, while a minimum of 9 applications of the 20% solution and 14 of the 5% solution caused similar reactions. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802140 |
| Origin |
NTIS |
| Type |
CAT |
