| Main Title |
Toxicity and Health Hazard Summary with Cover Letter. |
| CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1966 |
| Report Number |
878214645 |
| Stock Number |
OTS-0206606 |
| Additional Subjects |
Toxicity ;
Health effects ;
Acute ;
Mammals ;
Guinea pigs ;
Laboratory animals ;
Rats ;
Oral ;
Parenteral ;
Dermal ;
Inhalation ;
Intraperitoneal ;
2-ethyl hexanoic acid ;
CAS No 149-57-5 ;
Primary dermal irritation ;
Eastman Kodak Company
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206606 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
This is slightly toxic orally having an LD(sub 50) in rats of 1600-3200 mg/kg and in guinea pigs of 800-1600 mg/kg. The intraperitoneal LD(sub 50) is 800-1600 mg/kg in rats and 200-400 mg/kg in guinea pigs. It is a slight skin irritant when held in occluded contact with skin for 24 hours. It is absorbed through the skin .causing death at less than 5 ml/kg in guinea pigs. Inhalation of heated vapors at 400 ppm (calculated) caused no death in rats. Smyth gives the rat oral LD(sub 50) as 3 g/kg and the guinea pig skin LD(sub 50) at 6.3 ml/kg. Saturated vapor exposure for 8 hours caused no deaths. Severe eye irritation resulted in rabbits. This acid appears to be generally of low toxicity. Corneal damage may result from contact and skin absorption can occur. No data is available on the effects of repeated doses or on warning properties of the vapor. By analogy to related aliphatic acids it could be assumed that cumulative toxicity would not be great. The low volatility limits the hazard for use at room temperature. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2 Aug 1966 |
| Category Codes |
57Y |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019001750 |
| Origin |
NTIS |
| Type |
CAT |
