| Main Title |
Tests on the Comparative Toxicity of Acetic Acid Esters via Inhalation in Dogs with Cover Letter dated 03/30/94. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1994 |
| Report Number |
8EHQ-86940000298 |
| Stock Number |
OTS0572401 |
| Additional Subjects |
Toxicology ;
Health effects ;
Methyl acetate ;
Toxicity ;
Subchronic toxicity ;
Mammals ;
Dogs ;
Inhalation ;
CAS No 79-20-9 ;
CAS No 123-86-4 ;
CAS No 141-78-6 ;
Toxic substances ;
Laboratory animals
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0572401 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
Literature on the toxicity of esters of acetic acid compares them only on the basis of the atmospheric concentration required to produce muscular incoordination or narcosis. On this basis, methyl acetate is the least hazardous of the first four members of the series -- methyl, ethyl, propyl and butyl acetates. However, this comparison fails to take into account other physiological actions which accompany the effect of the esters on the nervous system. Narcosis may be preceded by, or itself involve, drastic changes in circulation or serious irritation of mucous membranes or the respiratory or gastro-enteric tracts. To obtain information rapidly to decide upon the suitability of methyl acetate, as compared with other acetates, as a component of a mixed solvent, dogs vere expoeod for repeated short periods, to concentrations of methyl, ethyl and butyl acetates, corresponding to half the narcotic concentrations. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
Mar 1994 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010501390 |
| Origin |
NTIS |
| Type |
CAT |
