| Main Title |
Support: Letter from Dow Corning Corp. to USEPA re: Repeat Insult Patch Test of DC 3-8015 Int (Platinum 2) and DC 2-0707 Int (Platinum 4) in Human Subjects, dated 09/28/1998. |
| CORP Author |
Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1998 |
| Report Number |
8EHQ-1098-13846 |
| Stock Number |
OTS0559082-1 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Platinum 2 ;
Platinum 4 ;
Primary dermal sensitization ;
Mammals ;
Humans ;
Dermal ;
CAS No 2627-95-4 ;
CAS No 68083-19-2 ;
CAS No 68478-92-2
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0559082-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
As was previously reported in our TSCA Section 8(e) Notifications of Substantial Risk of December 27, 1996, guinea pig maximization studies were conducted to determine the dermal sensitization potential of DOW CORNING(reg.) 3-8015 Int (Platinum 2) and DOW CORNING(reg.) 2-0707 Int (Platinum 4). In both studies, all positive control animals exhibited a positive reaction at the DNCB challenge control site with a severity index of 3.40 and no skin sensitization response was observed in the vehicle control animals. DOW CORNING(reg.) 3-8015 Int (Platinum 2) gave a positive response with an incidence and severity of 50% and 1.10, respectively, at the forty-eight hour scoring interval following the second challenge dose. DOW CORNING(reg.) 2-0707 Int (Platinum 4) gave a positive response with an incidence and severity of 55% and 1.10, respectively, at the forty-eight hour scoring interval following the second challenge dose. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
5 Oct 1998 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010501710 |
| Origin |
NTIS |
| Type |
CAT |
