| Main Title |
Behavioral Effects of Prenatal and Early Postnatal Lead Exposure in the Primate 'Macaca fascicularis'. |
| Author |
Hopper, D. L. ;
Kernan, W. J. ;
Lloyd, W. E. ;
|
| CORP Author |
Iowa State Univ., Ames.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1986 |
| Report Number |
EPA-68-03-2524; EPA/600/J-86/435; |
| Stock Number |
PB88-157714 |
| Additional Subjects |
Toxicology ;
Lead(Metal) ;
Behavior ;
Monkeys ;
Dosage ;
Exposure ;
Reprints ;
Macaca fascicularis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-157714 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
18p |
| Abstract |
Female Macaca fascicularis monkeys were given daily oral doses of 3.0 and 4.25 mg/kg lead, as lead nitrate, prior to breeding, and exposure was maintained throughout gestation and terminated at parturition. No overt signs of lead toxicity were observed in the maternal monkeys. The offspring were tested at 6 to 18 months of age on a three-choice non-spatial form discrimination paradigm, and at 19 to 26 months of age on a response inhibition task. When compared to controls, the lead-exposed infants showed a deficit in form discrimination performance which continued during the entire period of testing. A deficit in response inhibition performance was also observed in exposed infants when compared to controls. However, the deficit was temporary, as the performance of all groups was similar at the termination of testing. |
| Supplementary Notes |
Pub. in Toxicology and Industrial Health, v2 n1 p1-16 Apr 86. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Behavioral Effects of Prenatal and Early Postnatal Lead Exposure in the Primate 'Macaca fascicularis'. |
| PUB Date Free Form |
c1986 |
| Category Codes |
57Y |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
809818738 |
| Origin |
NTIS |
| Type |
CAT |
