| Main Title |
Initial Submission: Draft Pathology Report (Terminal Kill) in 13-Week Inhalation Toxicity Study in the Rat with 13-Week Treatment-Free Period, with Cover Letter dated 12/07/1999. (Sanitized). |
| CORP Author |
UOP, Inc., Des Plaines, IL.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1999 |
| Report Number |
8EHQ-1299-14613S |
| Stock Number |
OTS0559860 |
| Additional Subjects |
Pathology ;
Inhalation ;
Toxicity ;
Rats ;
Lungs ;
Lymph nodes ;
Dosage ;
Laboratory animals ;
Histopathology ;
Respiratory system ;
Treatment ;
Responses(Biology) ;
Morbidity ;
Mortality ;
Terminal kill
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0559860 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
148p |
| Abstract |
There were treatment-related changes in the lungs and bronchial lymph nodes of all treated group terminal kill animals. Microscopically, the findings in the lung were characterised by mild to moderate histiocytosis/proteinosis associated with perivascular cuffing/pneumonitis and increased peribronchial lymphoid response. Lymphoid hyperplasia and minor histiocyte foci were also found in the bronchial lymph nodes. A no observable effect level (NOEL) was not established. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
3 Nov 1999 |
| Category Codes |
57O; 57Y |
| NTIS Prices |
PC A08/MF A08 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010500890 |
| Origin |
NTIS |
| Type |
CAT |
